Intended Use :
This diagnostic reagent kit is used for detection of specific antibodies produced in response to the stimulation by specific antigen of Salmonella (group).
The killed bacterial suspension of Salmonella carries specific '0' and 'H' antigen. This will react with immunospecific antibodies which may be present in patient serum and agglutinate the antigen to produce agglutination or clumps on the slide.
The organism Salmonella typhosa is responsible for causing enteric fever or typhoid fever , which is characterized generally by very high consistent fever, loss of appetite, transitory bacteraemia, round or oval shaped ulcer on smooth peritoneal surface of Payer's patches and solitary lymphoid follicle of ileum etc. The organism possess 0' antigen on the cell wall and 'H' antigen on its flagella, against which the host body produces immuno specific antibodies, to counteract the effect of corresponding antigens. On the other hand the paratyphoid fever caused by Salmonella paratyphi A or Salmonella paratyphl B is characterized by milder course of disease. These organisms also possess somatic '0' and flagellar antigen which is termed as A(H) and B(H) respectively. The other organisms of Salmonella species like Salmonella typhimurium responsible for causing food poisoning or Arizona group causing fetal infection do have similar antigenic properties.
MOQ: 50 to 100 kits